Mounjaro (Tirzepatide)

Purpose

Mounjaro is a prescription medication containing the active ingredient tirzepatide. It is primarily designed for weight management in individuals with obesity (BMI ≥30) or severe overweight (BMI ≥27 with related conditions such as hypertension or prediabetes). This medication is classified as an incretin mimetic, which helps by regulating appetite and improving metabolic processes.

How It Works

Mounjaro operates through a dual-action mechanism, targeting the GLP-1 and GIP receptors. These receptors mimic gut hormones responsible for controlling blood sugar and feelings of satiety. Its functions include:

• Reducing hunger to support calorie control.
• Improving insulin sensitivity, enhancing blood sugar management.
• Delaying stomach emptying, which helps extend the feeling of fullness.
• Regulating glucose levels, reducing the risk of hyperglycemia.

Usage

• Administration: Mounjaro is administered as an injectable pen, used once weekly through a subcutaneous injection.
• Effectiveness: Clinical trials report a weight loss of up to 22.5% of total body weight at the highest dose (15 mg). Optimal results are achieved when the medication is paired with dietary adjustments and increased physical activity.

Side Effects

Initial side effects are common as the body adjusts to Mounjaro. These include:

• Nausea
• Vomiting
• Diarrhea
• Constipation

Symptoms are typically mild and temporary. To manage these effects, maintain adequate hydration and make appropriate dietary modifications.

Available Dosages

Mounjaro is offered in six dosage levels:

• 2.5 mg
• 5 mg
• 7.5 mg
• 10 mg
• 12.5 mg
• 15 mg

Treatment begins with the lowest dose, which is then gradually increased based on individual tolerability and treatment outcomes.